Structure of PDB 6dmy Chain B

Receptor sequence
>6dmyB (length=151) Species: 9606 (Homo sapiens) [Search protein sequence]
LTPLAYKQFIPNVAEKTLGASGRYEGKISRNSERFKELTPNYNPDIIFKD
EENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEES
LHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKAE
N
3D structure
PDB6dmy Structural basis for the recognition of Sonic Hedgehog by human Patched1.
ChainB
Resolution3.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SER B K186 N189 K148 N151
BS02 ZN B H140 D147 H182 H102 D109 H144
BS03 CA B E90 D129 E52 D91
BS04 CA B E89 D95 T125 E126 E51 D57 T87 E88
Gene Ontology
Biological Process
GO:0007267 cell-cell signaling
GO:0007275 multicellular organism development

View graph for
Biological Process
External links
PDB RCSB:6dmy, PDBe:6dmy, PDBj:6dmy
PDBsum6dmy
PubMed29954986
UniProtQ15465|SHH_HUMAN Sonic hedgehog protein (Gene Name=SHH)

[Back to BioLiP]