Structure of PDB 6dig Chain B

Receptor sequence
>6digB (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]
SPEDFVFQFKGMCYFTNGTERVRLVTRYIYNREEYARFDSDVGVYRAVTP
QGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAFRGILQRRVEPTVTIS
PSNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVM
LEMTPQRGDVYTCHVEHPSLQSPITVEWRA
3D structure
PDB6dig In vivo clonal expansion and phenotypes of hypocretin-specific CD4+T cells in narcolepsy patients and controls.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B F11 Y30 Y37 Y47 D57 Y60 W61 E74 T77 V78 H81 N82 F9 Y28 Y35 Y45 D55 Y58 W59 E72 T75 V76 H79 N80
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6dig, PDBe:6dig, PDBj:6dig
PDBsum6dig
PubMed31748512
UniProtQ5SU54

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