Structure of PDB 6d9s Chain B

Receptor sequence
>6d9sB (length=180) Species: 1392 (Bacillus anthracis) [Search protein sequence]
AMMNQDIEKVLISEEQIQEKVLELGAIIAEDYKNTVPLAIGVLKGAMPFM
ADLLKRTDTYLEMDFMAVSSYGHSTVSTGEVKILKDLDTSVEGRDILIVE
DIIDSGLTLSYLVDLFKYRKAKSVKIVTLLDKPTGRKVDLKADYVGFTVP
HEFVVGYGLDYKEQYRNLPYVGVLKPSVYS
3D structure
PDB6d9s Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction.
ChainB
Resolution2.105 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E99 D100 D103 F152 R165
Catalytic site (residue number reindexed from 1) E100 D101 D104 F153 R166
Enzyme Commision number 2.4.2.8: hypoxanthine phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G4P B K43 G44 I101 D103 S104 G105 K131 F152 V153 L158 D159 R165 K44 G45 I102 D104 S105 G106 K132 F153 V154 L159 D160 R166
BS02 MG B D159 R165 D160 R166
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0004422 hypoxanthine phosphoribosyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding
GO:0052657 guanine phosphoribosyltransferase activity
Biological Process
GO:0006166 purine ribonucleoside salvage
GO:0006178 guanine salvage
GO:0032263 GMP salvage
GO:0032264 IMP salvage
GO:0046100 hypoxanthine metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:6d9s, PDBe:6d9s, PDBj:6d9s
PDBsum6d9s
PubMed31552824
UniProtB9ZW32

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