Structure of PDB 6d4a Chain B

Receptor sequence
>6d4aB (length=124) Species: 9606 (Homo sapiens) [Search protein sequence]
DPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFREGAII
SRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYF
FRMERGSTKYSYKSPQLSVHVTDL
3D structure
PDB6d4a Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes A beta Phagocytosis.
ChainB
Resolution1.751 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FVP B F21 F117 R119 K126 Y127 S128 Y129 K130 F4 F100 R102 K109 Y110 S111 Y112 K113 MOAD: Kd=118uM
External links
PDB RCSB:6d4a, PDBe:6d4a, PDBj:6d4a
PDBsum6d4a
PubMed31369984
UniProtP20138|CD33_HUMAN Myeloid cell surface antigen CD33 (Gene Name=CD33)

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