Structure of PDB 6d12 Chain B

Receptor sequence
>6d12B (length=103) Species: 9606 (Homo sapiens) [Search protein sequence]
ATGPQFVSGVIVKIISTEPLPGRKQVRDTMAAISEVLYVDLLEGDTECHA
RFKTPLDALAVINAYTEINKKHCWKMEILSGDHEQRYWQKILVDRQAKLN
QPR
3D structure
PDB6d12 Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7.
ChainB
Resolution2.205 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B P449 R468 R472 L482 Y483 V484 D485 R496 Y532 I536 D539 R540 K543 L544 R548 P4 R23 R27 L37 Y38 V39 D40 R51 Y87 I91 D94 R95 K98 L99 R103 PDBbind-CN: Kd=129nM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:6d12, PDBe:6d12, PDBj:6d12
PDBsum6d12
PubMed29946027
UniProtQ4G0J3|LARP7_HUMAN La-related protein 7 (Gene Name=LARP7)

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