Structure of PDB 6d0f Chain B

Receptor sequence
>6d0fB (length=217) Species: 9606 (Homo sapiens) [Search protein sequence]
ALSLTADQMVSALLDAEPPILYSEFSEASMMGLLTNLADRELVHMINWAK
RVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDR
NQGKCVMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFDHI
HRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHL
YSMKPLSDLLLEMLDAH
3D structure
PDB6d0f Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with 3OHTPE and GRIP Peptide
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B I358 L372 V376 L539 E542 I46 L60 V64 L209 E212
BS02 FYS B A350 E353 L387 F404 L525 A38 E41 L75 F92 L200
External links
PDB RCSB:6d0f, PDBe:6d0f, PDBj:6d0f
PDBsum6d0f
PubMed
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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