Structure of PDB 6cz6 Chain B

Receptor sequence
>6cz6B (length=328) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
MPFEEVRDFFYDRNNYIHDLDMAAERMFTESGMRTGGLDIQLAELMRDRF
GISVVIDDNLPDTAKRRYHPDTKVLRVAHWLMPGQRAFQIATQLALVGQS
DLISSIVATDDQLSTEARGVARIGLANYFAGAFLLPYREFHRAAEQLRYD
IDLLGRRFGVGFETVCHRLSTLQRPRQRGIPFIFIRTDKAGNISKRQSAT
AFHFSRVGGSCPLWVVHDAFAQPERIVRQVAQMPDGRSYFWVAKTTAADG
LGYLGPHKNFAVGLGCDLAHAHKLVYSTGVVLDDPSTEVPIGAGCKICNR
TSCAQRAFPYLGGRVAVDENAGSSLPYS
3D structure
PDB6cz6 Structural and functional insight into the Mycobacterium tuberculosis protein PrpR reveals a novel type of transcription factor.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA B Q237 F240 G276 N279 Y280 E315 T316 H319 R338 K347 Q85 F88 G124 N127 Y128 E163 T164 H167 R186 K195
BS02 SF4 B C363 P364 L365 I443 G444 G446 C447 C450 C455 R458 C211 P212 L213 I291 G292 G294 C295 C298 C303 R306
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:6cz6, PDBe:6cz6, PDBj:6cz6
PDBsum6cz6
PubMed31504787
UniProtO06581|PRPR_MYCTU HTH-type transcriptional regulator PrpR (Gene Name=prpR)

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