Structure of PDB 6cyj Chain B

Receptor sequence
>6cyjB (length=329) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
PMPHEEVRDFFYDRNNYIHDLDMAAERMFTESGMRTGGLDIQLAELMRDR
FGISVVIDDNLPDTAKRRYHPDTKVLRVAHWLMPGQRAFQIATQLALVGQ
SDLISSIVATDDQLSTEARGVARIGLANYFAGAFLLPYREFHRAAEQLRY
DIDLLGRRFGVGFETVCHRLSTLQRPRQRGIPFIFVRTDKAGNISKRQSA
TAFHFSRVGGSCPLWVVHDAFAQPERIVRQVAQMPDGRSYFWVAKTTAAD
GLGYLGPHKNFAVGLGCDLAHAHKLVYSTGVVLDDPSTEVPIGAGCKICN
RTSCAQRAFPYLGGRVAVDENAGSSLPYS
3D structure
PDB6cyj Structural and functional insight into the Mycobacterium tuberculosis protein PrpR reveals a novel type of transcription factor.
ChainB
Resolution2.699 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SCA B P478 Y479 P327 Y328
BS02 SF4 B C363 P364 I443 G444 G446 C447 C450 C455 Q457 R458 C212 P213 I292 G293 G295 C296 C299 C304 Q306 R307
BS03 SCA B H155 R159 Q237 F240 N279 E315 T316 H319 R338 S346 K347 H4 R8 Q86 F89 N128 E164 T165 H168 R187 S195 K196
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:6cyj, PDBe:6cyj, PDBj:6cyj
PDBsum6cyj
PubMed31504787
UniProtO06581|PRPR_MYCTU HTH-type transcriptional regulator PrpR (Gene Name=prpR)

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