Structure of PDB 6cy8 Chain B

Receptor sequence
>6cy8B (length=370) Species: 717774 (Marinomonas mediterranea MMB-1) [Search protein sequence]
MNFEWTHEQAELFEHALRFGKELGFPRDNWNALGDFGYFGLPIPEKYAKD
GSGFDILTTIKIIEGLGQSCTDTGLLFAGAAHTFACSMPILEHGSETLKH
QLLPDLATKIAANAISEASAGSDISNLATTAQKEGDYYVLNGGKSYVTNG
SIADYYVVYATTNKKHGYLGQTAFVVPRNTPGISVGNDYHKLGLRSAPLN
QVFFDNCTIHKDYALGREGQGARIFAASMDWERCCLFAIFVGAMQRDLNQ
CIEYANTRMQGDKTISRFQAVSHRIADMGVRLESARLMLYYAAWQKSQDV
DNTKAVAMSKLAISEAFVQSGIDSIRVHGALGYLDEGRVNNSIKDALGSV
LFSGTSDIQRELICNRLGLL
3D structure
PDB6cy8 Insights into Thiotemplated Pyrrole Biosynthesis Gained from the Crystal Structure of Flavin-Dependent Oxidase in Complex with Carrier Protein.
ChainB
Resolution2.729 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) I125 S126 E242 N375
Catalytic site (residue number reindexed from 1) I115 S116 E232 N365
Enzyme Commision number 1.3.8.1: short-chain acyl-CoA dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD B N123 I125 S126 G131 S132 Y156 T158 L209 L361 F362 T365 D367 I368 N113 I115 S116 G121 S122 Y146 T148 L199 L351 F352 T355 D357 I358
BS02 PNS B S132 F235 A236 R243 S363 G364 S122 F225 A226 R233 S353 G354
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003995 acyl-CoA dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0016937 short-chain fatty acyl-CoA dehydrogenase activity
GO:0050660 flavin adenine dinucleotide binding

View graph for
Molecular Function
External links
PDB RCSB:6cy8, PDBe:6cy8, PDBj:6cy8
PDBsum6cy8
PubMed30620182
UniProtF2K077

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