Structure of PDB 6cwp Chain B

Receptor sequence
>6cwpB (length=307) Species: 376686 (Flavobacterium johnsoniae UW101) [Search protein sequence]
LVPRGSHMSIFDKRVNYKPFEYPEVLQFTEAINKAYWVHTEVDFTADTQD
FHAHLSLAEKTAVKNSLLAIAQIEVAVKSFWGNIYEHFPKPEFNGLGSTF
AECEFRHSEAYSRLLEVLGYNDEFEKLLDVPVIRRRVDYLSNVLKDTKSQ
DNRKYMVSLILFSILIENVSLFSQFAILLSFTRFKGYMKNVSNIIAWTSI
DEQIHANGGIYIINKIREEFPDYFDEETLALVRETVKDSIAVESDILDWI
FEEGEIESIKKGDLVNFMKFRIDESLKQINIPVIFDVKVEDYKALAWFEE
EVFANSL
3D structure
PDB6cwp Structural Basis for Superoxide Activation of Flavobacterium johnsoniae Class I Ribonucleotide Reductase and for Radical Initiation by Its Dimanganese Cofactor.
ChainB
Resolution1.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.17.4.1: ribonucleoside-diphosphate reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B M1 K6 R7 V8 N9 P12 E14 M8 K13 R14 V15 N16 P19 E21
BS02 MN B E67 E97 H100 E195 E74 E104 H107 E202
BS03 MN B E97 E160 E195 H198 E104 E167 E202 H205
Gene Ontology
Molecular Function
GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0009263 deoxyribonucleotide biosynthetic process
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:6cwp, PDBe:6cwp, PDBj:6cwp
PDBsum6cwp
PubMed29609464
UniProtA5FCJ5

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