Structure of PDB 6csp Chain B

Receptor sequence
>6cspB (length=358) Species: 7955 (Danio rerio) [Search protein sequence]
SPITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIP
ARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYT
CALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAA
LTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDG
AFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIA
REFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLII
LEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAH
APFWSSLR
3D structure
PDB6csp Entropy as a Driver of Selectivity for Inhibitor Binding to Histone Deacetylase 6.
ChainB
Resolution1.237 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B D612 H614 D705 D172 H174 D265
BS02 FBM B H573 H574 G582 F583 D612 H614 F643 L712 Y745 H133 H134 G142 F143 D172 H174 F203 L272 Y305 MOAD: Kd=3nM
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