Structure of PDB 6cs3 Chain B

Receptor sequence
>6cs3B (length=240) Species: 42789 (enterovirus D68) [Search protein sequence]
GVPTYLLPGSGQFLTTDDHSSAPALPCFNPTPEMHIPGQVRNMLEVVQVE
SMMEINNTESAVGMERLKVDISALTDVDQLLFNIPLDIQLDGPLRNTLVG
NISRYYTHWSGSLEMTFMFCGSFMAAGKLILCYTPPGGSCPTTRETAMLG
THIVWDFGLQSSVTLIIPWISGSHYRMFNNNANVGYVTCFMQTNLIVPSE
SSDTCSLIGFIAAKDDFSLRLMRDSPDIGQHLHAAEAAYQ
3D structure
PDB6cs3 Molecular basis for the acid-initiated uncoating of human enterovirus D68.
ChainB
Resolution3.31 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B D18 S20 S21 A22 P23 L25 C27 R41 N42 E45 Q48 D18 S20 S21 A22 P23 L25 C27 R41 N42 E45 Q48
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:6cs3, PDBe:6cs3, PDBj:6cs3
PDBsum6cs3
PubMed30530701
UniProtA0A097BW12

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