Structure of PDB 6cpn Chain B

Receptor sequence
>6cpnB (length=189) Species: 9606 (Homo sapiens) [Search protein sequence]
DTRPRFLEYSTSECHFFNGTERVRFLDRYFYNQEEYVRFDSDVGEFRAVT
ELGRPDEEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTVQRRVHPKVTV
YPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG
DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
3D structure
PDB6cpn CD4+T cell-mediated HLA class II cross-restriction in HIV controllers.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B S13 F26 D57 Y60 W61 F67 D70 R71 Y78 H81 N82 V85 S12 F25 D56 Y59 W60 F66 D69 R70 Y77 H80 N81 V84
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6cpn, PDBe:6cpn, PDBj:6cpn
PDBsum6cpn
PubMed29884618
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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