Structure of PDB 6cpl Chain B

Receptor sequence
>6cplB (length=189) Species: 9606 (Homo sapiens) [Search protein sequence]
DTRPRFLEYSTSECHFFNGTERVRFLDRYFYNQEEYVRFDSDVGEFRAVT
ELGRPDEEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTVQRRVHPKVTV
YPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG
DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
3D structure
PDB6cpl CD4+T cell-mediated HLA class II cross-restriction in HIV controllers.
ChainB
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B S13 F26 P56 D57 Y60 W61 F67 R71 T77 Y78 H81 N82 V85 S12 F25 P55 D56 Y59 W60 F66 R70 T76 Y77 H80 N81 V84
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6cpl, PDBe:6cpl, PDBj:6cpl
PDBsum6cpl
PubMed29884618
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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