Structure of PDB 6co9 Chain B

Receptor sequence
>6co9B (length=247) Species: 101510 (Rhodococcus jostii RHA1) [Search protein sequence]
EVTRAEYCAIACADIFSGAGEIMASPMATLPLIGARLARLTTEPDLLITD
GEALIFADTPAVGAKAPIEGWMPFRKVFDVVASGRRHVVMGANQIDRHGN
QNLSAFGPLQQPTRQMFGVRGAPGNTINHPTSYWVGKHTSRVFCDTVDIV
SGVGYDQIDPENPAYRFHHLHRVVSNLGVFDFGGPDHTFRALSLHPGVTA
DQVADNTSFEVAGLADAGVTREPTDEELRLIREVLDPRSLRDREVSV
3D structure
PDB6co9 IpdAB, a virulence factor inMycobacterium tuberculosis, is a cholesterol ring-cleaving hydrolase.
ChainB
Resolution1.602 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.99.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 F8G B M33 F84 R92 M96 G97 A98 N99 L109 F112 T119 R120 R126 N131 M27 F78 R86 M90 G91 A92 N93 L103 F106 T113 R114 R120 N125
Gene Ontology
Biological Process
GO:0006707 cholesterol catabolic process
GO:0008203 cholesterol metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6co9, PDBe:6co9, PDBj:6co9
PDBsum6co9
PubMed29581275
UniProtQ0S7Q0|IPDB_RHOJR Cholesterol ring-cleaving hydrolase IpdB subunit (Gene Name=ipdB)

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