Structure of PDB 6cl1 Chain B

Receptor sequence
>6cl1B (length=91) Species: 9606 (Homo sapiens) [Search protein sequence]
KIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQI
LTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFS
3D structure
PDB6cl1 Selective and Rapid Cell-Permeable Inhibitor of Human Caspase-3.
ChainB
Resolution2.651 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.60: caspase-7.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B Y230 S231 W232 R233 Y19 S20 W21 R22
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function

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Biological Process
External links
PDB RCSB:6cl1, PDBe:6cl1, PDBj:6cl1
PDBsum6cl1
PubMed31334631
UniProtP55210|CASP7_HUMAN Caspase-7 (Gene Name=CASP7)

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