Structure of PDB 6cl0 Chain B

Receptor sequence
>6cl0B (length=104) Species: 9606 (Homo sapiens) [Search protein sequence]
SGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQ
YADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYF
YHLE
3D structure
PDB6cl0 Selective and Rapid Cell-Permeable Inhibitor of Human Caspase-3.
ChainB
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y204 S205 W206 R207 N208 S209 S249 F250 F256 Y29 S30 W31 R32 N33 S34 S74 F75 F81
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6cl0, PDBe:6cl0, PDBj:6cl0
PDBsum6cl0
PubMed31334631
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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