Structure of PDB 6cja Chain B

Receptor sequence
>6cjaB (length=381) Species: 272624 (Legionella pneumophila subsp. pneumophila str. Philadelphia 1) [Search protein sequence]
KTHFDTRAIHAGQEPCKSTGAVMTPIYATSTYKQIAPGEHLGYEYSRTQN
PTRKAYEDCIASLESGQKGFAFASGMAAINTVIDLLGSGDHVVAMDDLYG
GTFRLFDKVKTRTSNLSFSFIDMSVPENIEAAITPKTKLLWLETPSNPML
KLANLRKIAAIAKKYNLITVADNTFATPWIQRPLELGFDIVLHSATKYLN
GHSDVVSGVVVVGDNSVLSDKIAFLQNSCGAVAGPFDSFLVLRSLKTLSV
RMQRHCENANHLANWLSSHPKIEKVIYPGLKSHPQYSLAKEQMNNFGGMI
SLVLKGSLEDAKRFLARCELFTLAESLGGVESLIEHPAIMTHASIPVEQR
KALGIEDGFIRLSVGIEHIDDLRADLEHALG
3D structure
PDB6cja Crystal structure of Cystathionine beta-lyase from Legionella pneumophila Philadelphia 1 in complex with Alanyl-PLP and Serine
ChainB
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.4.1.8: Transferred entry: 4.4.1.13.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 F0G B Y47 R49 Y45 R47
BS02 SER B E46 R49 T50 E44 R47 T48
BS03 SER B Y101 R106 E327 Y99 R104 E325
BS04 F0G B S76 G77 M78 Y101 N149 D174 S196 T198 K199 S328 T343 R363 S74 G75 M76 Y99 N147 D172 S194 T196 K197 S326 T341 R361
Gene Ontology
Molecular Function
GO:0003962 cystathionine gamma-synthase activity
GO:0016829 lyase activity
GO:0016846 carbon-sulfur lyase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0019346 transsulfuration
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6cja, PDBe:6cja, PDBj:6cja
PDBsum6cja
PubMed
UniProtQ5ZX43

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