Structure of PDB 6ch4 Chain B

Receptor sequence
>6ch4B (length=297) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
YDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTK
FSKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFL
TPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEY
ILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFNCNHLLL
DGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNI
DIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD
3D structure
PDB6ch4 Plasticity of Aminoglycoside Binding to Antibiotic Kinase APH(2′′)-Ia.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.7.1.190: aminoglycoside 2''-phosphotransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP B S214 I224 K226 Y274 E276 I277 F281 I392 D393 S36 I46 K48 Y92 E94 I95 F99 I210 D211
BS02 MG B H379 D393 H197 D211
External links
PDB RCSB:6ch4, PDBe:6ch4, PDBj:6ch4
PDBsum6ch4
PubMed29661878
UniProtP0A0C1|AACA_STAAU Bifunctional AAC/APH (Gene Name=aacA-aphD)

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