Structure of PDB 6cf6 Chain B

Receptor sequence
>6cf6B (length=319) Species: 10090 (Mus musculus) [Search protein sequence]
DPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTP
LHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLL
KHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAV
DMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSH
ETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHND
VMEVLHKHGAKMNALDSLGQTALHRAALAGHLQTCRLLLSYGSDPSIISL
QGFTAAQMGNEAVQQILSE
3D structure
PDB6cf6 Structural basis for tankyrase-RNF146 interaction reveals noncanonical tankyrase-binding motifs.
ChainB
Resolution1.93 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.4.2.-
2.4.2.30: NAD(+) ADP-ribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R361 S363 L368 G371 Y372 K393 N401 Y405 H407 D425 W427 F429 E434 R440 R46 S48 L53 G56 Y57 K78 N86 Y90 H92 D110 W112 F114 E119 R125
External links
PDB RCSB:6cf6, PDBe:6cf6, PDBj:6cf6
PDBsum6cf6
PubMed29604130
UniProtQ6PFX9|TNKS1_MOUSE Poly [ADP-ribose] polymerase tankyrase-1 (Gene Name=Tnks)

[Back to BioLiP]