Structure of PDB 6cc8 Chain B

Receptor sequence
>6cc8B (length=71) Species: 9606 (Homo sapiens) [Search protein sequence]
MERKRWECPALPQGWEREEVPRRSGLSAGHRDVFYYSPSGKKFRSKPQLA
RYLGGSMDLSTFDFRTGKMLM
3D structure
PDB6cc8 Structural analyses reveal that MBD3 is a methylated CG binder.
ChainB
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B R22 R23 S24 L26 S27 K42 R22 R23 S24 L26 S27 K42 PDBbind-CN: Kd=5.4uM
BS02 dna B R44 S45 R65 R44 S45 R65 PDBbind-CN: Kd=5.4uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6cc8, PDBe:6cc8, PDBj:6cc8
PDBsum6cc8
PubMed30980593
UniProtO95983|MBD3_HUMAN Methyl-CpG-binding domain protein 3 (Gene Name=MBD3)

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