Structure of PDB 6c6k Chain B

Receptor sequence
>6c6kB (length=454) Species: 9606 (Homo sapiens) [Search protein sequence]
DHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHN
LLAYVKHLKGQNEEALKSLKEAENLMQNVRSLVTWGNFAWMYYHMGRLAE
AQTYLDKVENICKSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFE
KVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPD
NGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKG
SVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNR
EKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQK
LLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTR
DKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALR
LAAD
3D structure
PDB6c6k Human IFIT3 Modulates IFIT1 RNA Binding Specificity and Protein Stability.
ChainB
Resolution2.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0009615 response to virus
GO:0019060 intracellular transport of viral protein in host cell
GO:0032091 negative regulation of protein binding
GO:0045070 positive regulation of viral genome replication
GO:0045071 negative regulation of viral genome replication
GO:0045087 innate immune response
GO:0051097 negative regulation of helicase activity
GO:0051607 defense response to virus
GO:0051707 response to other organism
GO:0071357 cellular response to type I interferon
GO:0071360 cellular response to exogenous dsRNA
GO:0140374 antiviral innate immune response
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0043657 host cell

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6c6k, PDBe:6c6k, PDBj:6c6k
PDBsum6c6k
PubMed29525521
UniProtP09914|IFIT1_HUMAN Interferon-induced protein with tetratricopeptide repeats 1 (Gene Name=IFIT1)

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