Structure of PDB 6c1v Chain B

Receptor sequence
>6c1vB (length=68) Species: 9606 (Homo sapiens) [Search protein sequence]
GKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARY
LGNTVDLSSFDFRTGKMM
3D structure
PDB6c1v Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.
ChainB
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B R166 S168 G169 L170 S171 R20 S22 G23 L24 S25 PDBbind-CN: Kd=13uM
BS02 dna B R188 S189 P191 R209 R42 S43 P45 R63 PDBbind-CN: Kd=13uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6c1v, PDBe:6c1v, PDBj:6c1v
PDBsum6c1v
PubMed29567833
UniProtQ9UBB5|MBD2_HUMAN Methyl-CpG-binding domain protein 2 (Gene Name=MBD2)

[Back to BioLiP]