Structure of PDB 6c1r Chain B

Receptor sequence
>6c1rB (length=371) Species: 562,9606 [Search protein sequence]
LEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAKDFRHGFDILVG
QIDDALKLANEGKVKEAQAAAEQLKTTRNAYSNTLRVPDILALVIFAVVF
LVGVLGNALVVWVTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQ
HHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPIWCQNFR
GAGLAWIACAVAWGLALLLTIPSFLYRVVREEYFPPKVLCGVDYSHDKRR
ERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRSTKTLKVVVAVVASF
FIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIYV
VAGQGFKSLPSLLRNVLTEES
3D structure
PDB6c1r Orthosteric and allosteric action of the C5a receptor antagonists.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B L178 S181 P199 R261 R264 C274 G275 V276 S279 Y344 G348 M351 K365 D368 V372 L144 S147 P165 R227 R230 C240 G241 V242 S245 Y307 G311 M314 K328 D331 V335
BS02 EFD B L211 A214 A218 F221 L295 W299 T303 C307 L177 A180 A184 F187 L261 W265 T269 C273
Gene Ontology
Molecular Function
GO:0004875 complement receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006935 chemotaxis
GO:0007186 G protein-coupled receptor signaling pathway
GO:0022900 electron transport chain
Cellular Component
GO:0016020 membrane
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6c1r, PDBe:6c1r, PDBj:6c1r
PDBsum6c1r
PubMed29867214
UniProtP0ABE7|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
P21730|C5AR1_HUMAN C5a anaphylatoxin chemotactic receptor 1 (Gene Name=C5AR1)

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