Structure of PDB 6c1q Chain B

Receptor sequence
>6c1qB (length=374) Species: 562,9606 [Search protein sequence]
DLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDASPEMKDFRHGF
DILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYTLRVPDILAL
VIFAVVFLVGVLGNALVVWVTAFEAKRTINAIWFLNLAVADFLSCLALPI
LFTSIVQHHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKP
IWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREEYFPPKVLCGVD
YSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRSTKTLKVVV
AVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCI
NPIIYVVAGQGFQSLPSLLRNVLT
3D structure
PDB6c1q Orthosteric and allosteric action of the C5a receptor antagonists.
ChainB
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B L178 P199 R261 R264 C274 G275 V276 S279 Y344 D368 V372 L151 P172 R234 R237 C247 G248 V249 S252 Y313 D337 V341
BS02 9P2 B I210 L211 A214 T215 V245 L249 L295 W299 P300 T303 I183 L184 A187 T188 V218 L222 L268 W272 P273 T276
Gene Ontology
Molecular Function
GO:0004875 complement receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006935 chemotaxis
GO:0007186 G protein-coupled receptor signaling pathway
GO:0022900 electron transport chain
Cellular Component
GO:0016020 membrane
GO:0042597 periplasmic space

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Biological Process
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Cellular Component
External links
PDB RCSB:6c1q, PDBe:6c1q, PDBj:6c1q
PDBsum6c1q
PubMed29867214
UniProtP0ABE7|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
P21730|C5AR1_HUMAN C5a anaphylatoxin chemotactic receptor 1 (Gene Name=C5AR1)

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