Structure of PDB 6bzr Chain B

Receptor sequence
>6bzrB (length=237) Species: 9606 (Homo sapiens) [Search protein sequence]
GGQIEFRDFGLRYRPELPLAVQGVSFKIHAGEKVGIVGRTGAGKSSLASG
LLRLQEAAEGGIWIDGVPIAHVGLHTLRSRISIIPQDPILFPGSLRMNLD
LLQEHSDEAIWAALETVQLKALVASLPGQLQYKCDLSVGQKQLLCLARAL
LRKTQILILDEATAAVDPGTELQMQAMLGSWFAQCTVLLIAHRLRSVMDC
ARVLVMDKGQVAESGSPAQLLAQKGLFYRLAQESGLV
3D structure
PDB6bzr Structures of human ABCC6 NBD1 and NBD2
ChainB
Resolution2.79999 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.6.2.-
7.6.2.3: ABC-type glutathione-S-conjugate transporter.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B Y1274 A1281 G1302 G1304 K1305 S1306 S1307 Y13 A20 G41 G43 K44 S45 S46
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:6bzr, PDBe:6bzr, PDBj:6bzr
PDBsum6bzr
PubMed
UniProtO95255|MRP6_HUMAN ATP-binding cassette sub-family C member 6 (Gene Name=ABCC6)

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