Structure of PDB 6bzc Chain B

Receptor sequence

>6bzcB (length=546) Species: 1338011 (Elizabethkingia anophelis NUHP1)

SLNTINPTETKAWAQLKEHFAETDFDLKQLFTEDKSRFSEFSIQKENLLF
DFSKNLVDKKAFQLLLALAEECHLNDAIEKMFTGDLINQTENRAVLHTAL
RNFGEEKIVVNGKSIDEDVQRVLNQMKIFSEKIISGEHKGFSGKEITDVV
NIGIGGSDLGPVMVCSALKHYRTRLNTHFVSNVDGNHIAEVVKNLNPETT
LFIIASKTFTTQETMTNALSAKEWFLKAGKEEDVAKHFVALSTNIEAVKN
FGIAEENIFEFWDWVGGRYSLWSAIGLSIVLAVGYDNFEKLLRGAQDTDK
HFRNTEFKNNIPVLMGVLGVWYRNFFDASSYAILPYSQYLDRFAAYLQQG
DMESNGKSVDRNGEFVDYETGPIIWGEPGTNGQHAFYQLIHQGTELIPAD
FIAYAKANNNLSDHQDKLMSNFFAQTEALAFGKTKEQVITELKASGKNEE
EIAFLTNFKTFTGNTPTNSFIFEELTPFTLGQLIAFYEHKIFVQGVIWNI
FSFDQWGVELGKALANKILPELENTAEITSHDSSTNGLINFYKKHK

3D structure

• PDB: 6bzc Crystal Structure of Glucose-6-phosphate Isomerase from Elizabethkingia anophelis with bound Glucose-6-phosphate
• Chain: B
• Resolution: 2.05 Å

Enzymatic activity

• Enzyme Commision number: 5.3.1.9: glucose-6-phosphate isomerase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	G6P	B	I155 G157 S207 K208 T209 T212 Q350 E354	I154 G156 S206 K207 T208 T211 Q349 E353

Gene Ontology

Molecular Function

• GO:0004347 glucose-6-phosphate isomerase activity
• GO:0016853 isomerase activity
• GO:0048029 monosaccharide binding
• GO:0097367 carbohydrate derivative binding

Biological Process

• GO:0006094 gluconeogenesis
• GO:0006096 glycolytic process
• GO:0051156 glucose 6-phosphate metabolic process
• GO:1901135 carbohydrate derivative metabolic process

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol

External links

• PDB: RCSB:6bzc, PDBe:6bzc, PDBj:6bzc
• PDBsum: 6bzc
• UniProt: A0A077EQ93