Structure of PDB 6bz4 Chain B

Receptor sequence

>6bz4B (length=206) Species: 9606 (Homo sapiens) [Search protein sequence]

GPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHN
AKTKPREEQYNSTVVSVLTVLHQDWLNGKEYKCAVSNKALPAPIEKTISK
AKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPE
NNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQ
KSLSLS

3D structure

PDB

6bz4 Global conformational changes in IgG-Fc upon mutation of the FcRn-binding site are not associated with altered antibody-dependent effector functions.

Chain

Resolution

2.4 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	BMA	B	F241 F243	F5 F7

External links

PDB	RCSB:6bz4, PDBe:6bz4, PDBj:6bz4
PDBsum	6bz4
PubMed	29794155
UniProt	P0DOX5\|IGG1_HUMAN Immunoglobulin gamma-1 heavy chain

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