Structure of PDB 6bxm Chain B

Receptor sequence
>6bxmB (length=314) Species: 1392998 (Candidatus Methanoperedens nitroreducens) [Search protein sequence]
FDLERILKTIKDKNCKKVGLQFPEGLKRQAINIAREIEEKTRANVIISGN
PCFGACDIDTILAGSVDILFHFGHAGMGEYENVVFIEARSNIDIIPAVKT
ALNLLKANRIGLITTVQHVHKLEEACKVIKEYGKECVIGKPRAIYPGQVL
GCNFTAARVDCEEFIYIGSGIFHPLGVAIATKKRVIAADPFLNQAVEVSP
ERFLRKRGGYIAKATGAKIFGIIVSTKSGQYRMKLAQKLKEIADKHGKIG
YIILMDLVTPEQLLAFKADAYVNTACPRITIDDAERFHAPVLTPQEFEIV
LGERRWENMEMDEM
3D structure
PDB6bxm Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis.
ChainB
Resolution2.252 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.108: 2-(3-amino-3-carboxypropyl)histidine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 B C61 G158 C159 C283 R285 C56 G151 C152 C276 R278
BS02 ABA B L157 G158 H180 R285 L150 G151 H173 R278
BS03 MTA B F58 K234 Q237 L264 V265 C283 I286 D290 F53 K227 Q230 L257 V258 C276 I279 D283
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0090560 2-(3-amino-3-carboxypropyl)histidine synthase activity
Biological Process
GO:0017183 protein histidyl modification to diphthamide

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Molecular Function
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Biological Process
External links
PDB RCSB:6bxm, PDBe:6bxm, PDBj:6bxm
PDBsum6bxm
PubMed29590073
UniProtA0A062UZ78

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