Structure of PDB 6bn8 Chain B

Receptor sequence
>6bn8B (length=375) Species: 9606 (Homo sapiens) [Search protein sequence]
PNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIP
GQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYA
YREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPST
MSAVQLESLNKCQIFPCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAET
LMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIG
SAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNP
HGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKF
TATKKDMSPQKFWGLTRSALLPTIP
3D structure
PDB6bn8 Plasticity in binding confers selectivity in ligand-induced protein degradation.
ChainB
Resolution3.99004 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C323 C326 C391 C271 C274 C339
External links
PDB RCSB:6bn8, PDBe:6bn8, PDBj:6bn8
PDBsum6bn8
PubMed29892083
UniProtQ96SW2|CRBN_HUMAN Protein cereblon (Gene Name=CRBN)

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