Structure of PDB 6b9f Chain B

Receptor sequence
>6b9fB (length=422) Species: 9606 (Homo sapiens) [Search protein sequence]
KAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGK
SFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEIF
LINKPDGKKVAVLLMDTQGTSDSQSTLRDSATVFALSTMISSIQVYNLSQ
NVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGAD
GGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNP
NFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLVEYFK
AYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKP
FLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYI
QYIKHNDSKNIFHAARAAALEH
3D structure
PDB6b9f A hereditary spastic paraplegia-associated atlastin variant exhibits defective allosteric coupling in the catalytic core.
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B S81 T120 S51 T90
BS02 GDP B R77 G79 K80 S81 F82 W112 R113 G114 R217 D218 P272 V276 R47 G49 K50 S51 F52 W82 R83 G84 R187 D188 P242 V246
BS03 ALF B F76 R77 K80 E119 T120 G149 F46 R47 K50 E89 T90 G119
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:6b9f, PDBe:6b9f, PDBj:6b9f
PDBsum6b9f
PubMed29180453
UniProtQ8WXF7|ATLA1_HUMAN Atlastin-1 (Gene Name=ATL1)

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