Structure of PDB 6b9e Chain B

Receptor sequence
>6b9eB (length=387) Species: 9606 (Homo sapiens) [Search protein sequence]
VKKAGPVQVLIVKHSFELDETALNRILLSEAVRDKEVVAVSVAGAFAKGK
SFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRTTGIQIWSEIFLINKPD
GKKVAVLLMDTQLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFT
EYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSG
NQHEELQNVRKHIHSCFTNISCFLLPHPGLKVAFDGKLKEIDDEFIKNLK
ILIPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELPHPKSML
QATAEANNLAAVATAKDTYNKKMEEICPFLAPNDLQTKHLQLKEESVKLF
RGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSK
3D structure
PDB6b9e A hereditary spastic paraplegia-associated atlastin variant exhibits defective allosteric coupling in the catalytic core.
ChainB
Resolution1.99 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP B A77 K78 G79 K80 S81 F82 W112 Q148 R217 D218 P272 V276 A47 K48 G49 K50 S51 F52 W82 Q112 R173 D174 P228 V232
BS02 MG B D146 Q148 D110 Q112
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:6b9e, PDBe:6b9e, PDBj:6b9e
PDBsum6b9e
PubMed29180453
UniProtQ8WXF7|ATLA1_HUMAN Atlastin-1 (Gene Name=ATL1)

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