Structure of PDB 6awg Chain B

Receptor sequence
>6awgB (length=265) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
MKVGIDAGGTLIKIVQEQDQRTFKTELTKNIDQVVEWLNQQQIEKLCLTG
GNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGT
SLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNT
IDLKVRHIYKDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVG
EVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYV
ENGAFSGAIGALYLE
3D structure
PDB6awg Structure-based identification of uncompetitive inhibitors for Staphylococcus aureus pantothenate kinase.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.33: pantothenate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C0G B F71 G100 T101 R113 G116 I117 F70 G99 T100 R112 G115 I116
BS02 ADP B G8 G9 T10 L11 K13 G98 T99 G121 Q125 Y137 S225 S226 G8 G9 T10 L11 K13 G97 T98 G120 Q124 Y136 S224 S225
BS03 C0G B L171 T172 A173 E202 Y240 L170 T171 A172 E201 Y239
Gene Ontology
Molecular Function
GO:0004594 pantothenate kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
Biological Process
GO:0015937 coenzyme A biosynthetic process
GO:0016310 phosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6awg, PDBe:6awg, PDBj:6awg
PDBsum6awg
PubMed
UniProtQ2FWC7|COAW_STAA8 Type II pantothenate kinase (Gene Name=coaW)

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