Structure of PDB 6aom Chain B

Receptor sequence
>6aomB (length=213) Species: 9615 (Canis lupus familiaris) [Search protein sequence]
EKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDE
NALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTITSEFLNK
MTESTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVI
ADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWS
SKTKTVWDWELMN
3D structure
PDB6aom Second Generation Grp94-Selective Inhibitors Provide Opportunities for the Inhibition of Metastatic Cancer.
ChainB
Resolution2.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VC5 B N107 D110 A111 D149 M154 N162 F199 T245 I247 N34 D37 A38 D76 M81 N89 F116 T162 I164 BindingDB: Kd=630nM
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:6aom, PDBe:6aom, PDBj:6aom
PDBsum6aom
PubMed28857290
UniProtP41148|ENPL_CANLF Endoplasmin (Gene Name=HSP90B1)

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