Structure of PDB 6ank Chain B

Receptor sequence
>6ankB (length=263) Species: 10116 (Rattus norvegicus) [Search protein sequence]
NLGRIQFSVGYNFQESTLTVKVMKAQELPAKDFSGTSDPFVKIYLLPDKK
HKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDP
IGEVSIPLNKVDLTQMQTFWKDLKPSRGELLLSLCYNPSANSIIVNIIKA
RNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTKKRNLNPIFNESFAFD
IPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKHWKDMIAR
PRQPVAQWHQLKA
3D structure
PDB6ank Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
ChainB
Resolution2.254 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B D166 D172 D225 Y226 D227 D32 D38 D91 Y92 D93
BS02 CA B K165 D166 D225 D227 D233 K31 D32 D91 D93 D99
BS03 CA B D297 D303 D357 K358 D359 D157 D163 D217 K218 D219
BS04 CA B M296 D297 D357 D359 D365 M156 D157 D217 D219 D225
Gene Ontology
Molecular Function
GO:0005544 calcium-dependent phospholipid binding
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:6ank, PDBe:6ank, PDBj:6ank
PDBsum6ank
PubMed28923929
UniProtQ62747|SYT7_RAT Synaptotagmin-7 (Gene Name=Syt7)

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