Structure of PDB 6aim Chain B

Receptor sequence
>6aimB (length=309) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
EEEQYFKTNPKPAYIDELIKDAKEFIDLQYSLKRNKIVLITSGGTTVPLE
NNTVRFIDNFSAGTRGASSAEQFLANGYSVIFLHREFSLTPYNRSFSHSI
NTLFLDYIDSEGKIKPEFAENVLKNKKLYDKYMEKEEKLLLLPFTTVNQY
LWSLKSIAKLLNNSGCLFYLAAAVSDFFVPYSRLPQHKIQEGTTRTTPDG
KLIVNLDPVPKFLRRLVESWATQAMIVSFKLETDESMLLYKCTQALDRYN
HQLVIGNLLQTRNKQVIFVSPENRKGDWVRLDEKHASIEEMIIPEVIARH
DKWVAHSKT
3D structure
PDB6aim Crystallographic Analysis of the Catalytic Mechanism of Phosphopantothenoylcysteine Synthetase from Saccharomyces cerevisiae.
ChainB
Resolution2.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.5: phosphopantothenate--cysteine ligase (CTP).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9Z3 B S99 A100 G101 T102 R103 A209 A210 A211 F280 K281 L282 N308 R313 S61 A62 G63 T64 R65 A171 A172 A173 F229 K230 L231 N257 R262
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004632 phosphopantothenate--cysteine ligase activity
GO:0005515 protein binding
GO:0016874 ligase activity
Biological Process
GO:0015937 coenzyme A biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:1990143 CoA-synthesizing protein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6aim, PDBe:6aim, PDBj:6aim
PDBsum6aim
PubMed30653991
UniProtP40506|PPCS_YEAST Phosphopantothenate--cysteine ligase CAB2 (Gene Name=CAB2)

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