Structure of PDB 6agm Chain B

Receptor sequence
>6agmB (length=334) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
DALNNVHITDEQVLMTPEQLKAAFPLSLQQEAQIADSRKSISDIIAGRDP
RLLVVCGPCSIHDPETALEYARRFKALAAEVSDSLYLVMRVYFEKPRTTV
GWKGLINDPHMDGSFDVEAGLQIARKLLLELVNMGLPLATEALDPNSPQY
LGDLFSWSAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRA
AAQPHRFVGINQAGQVALLQTQGNPDGHVILRGGKAPNYSPADVAQCEKE
MEQAGLRPSLMVDCSHGNSNKDYRRQPAVAESVVAQIKDGNRSIIGLMIE
SNIHEGDACISWEMTDALLREIHQDLNGQLTARV
3D structure
PDB6agm Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TYR B P148 P151 Q152 L180 S181 F210 G212 I213 L222 P145 P148 Q149 L177 S178 F207 G209 I210 L219
Gene Ontology
Molecular Function
GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity
GO:0016740 transferase activity
GO:0042802 identical protein binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009058 biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:6agm, PDBe:6agm, PDBj:6agm
PDBsum6agm
PubMed30946901
UniProtP00888|AROF_ECOLI Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive (Gene Name=aroF)

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