Structure of PDB 6agi Chain B

Receptor sequence
>6agiB (length=322) Species: 9606 (Homo sapiens) [Search protein sequence]
IEDLDLYATSRERRFRLFASIECEGQLFMTPYDFILAVTTDEPKVAKWKS
LSKQELNQMLAETPPVWKGSSKLFRNLKEKGVISYTEYLFLLCILTKPHA
GFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIKGDEEKRAMLRL
QLYGYLVTDTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYS
NGMNTISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKGITFDEFRSFF
QFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKFSPHLVNTVFK
IFDVDKDDQLSYKEFIGIMKDR
3D structure
PDB6agi Dimerization of MICU Proteins Controls Ca2+Influx through the Mitochondrial Ca2+Uniporter.
ChainB
Resolution2.799 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA B D245 D247 N249 M251 D253 E256 D110 D112 N114 M116 D118 E121
BS02 CA B D483 D485 D487 Q489 E494 D303 D305 D307 Q309 E314
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0006851 mitochondrial calcium ion transmembrane transport

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Molecular Function

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Biological Process
External links
PDB RCSB:6agi, PDBe:6agi, PDBj:6agi
PDBsum6agi
PubMed30699349
UniProtQ86XE3|MICU3_HUMAN Calcium uptake protein 3, mitochondrial (Gene Name=MICU3)

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