Structure of PDB 6add Chain B

Receptor sequence
>6addB (length=166) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
PVVRRARTSDVPAIKQLVDTYAGKILLEKNLVTLYEAVQEFWVAEHPDLY
GKVVGCGALHVLWSDLGEIRTVAVDPAMTGHGIGHAIVDRLLQVARDLQL
QRVFVLTFETEFFARHGFTEIEGTPVTAEVFDEMCRSYDIGVAEFLDLSY
VKPNILGNSRMLLVLL
3D structure
PDB6add Structural insights into the substrate binding mechanism of novel ArgA from Mycobacterium tuberculosis
ChainB
Resolution2.301 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.1: amino-acid N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA B Y30 V81 A82 V83 T88 G89 H90 G91 G93 H94 T116 E118 F121 R124 Y21 V72 A73 V74 T79 G80 H81 G82 G84 H85 T107 E109 F112 R115
BS02 NLQ B K33 I34 L35 L36 R79 L115 E153 K24 I25 L26 L27 R70 L106 E144
Gene Ontology
Molecular Function
GO:0004042 L-glutamate N-acetyltransferase activity
GO:0008080 N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0042803 protein homodimerization activity
Biological Process
GO:0006526 L-arginine biosynthetic process
GO:0042450 arginine biosynthetic process via ornithine
GO:0051289 protein homotetramerization
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6add, PDBe:6add, PDBj:6add
PDBsum6add
PubMed30576731
UniProtO33289|ARGA_MYCTU Amino-acid acetyltransferase (Gene Name=argA)

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