Structure of PDB 6acx Chain B

Receptor sequence
>6acxB (length=1168) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
SVQTPIAGLVELALSDPSLQDVIRRAADRPADLALVGPASARVLVAAALA
QNGPLLVVAATGREADELTAELRGVFGDSVALFPSWETLPHERLSPGVET
VGARLMLLRRLARPDDETLGAPLRVVVTTTRSLLQPMAPDLVDIEPVTLS
VGAEMEFEDVVARLVDLSYTRVDMVGKRGEFAVRGGILDVFPPTAEHPVR
VEFWGDEISEMRAFAIADQRSIPEVPVQTVVAVPCRELLMTDDVRERAAA
LAAEHPTTENTVPGTVPDMLAKLAEGIPVDGMEALLPLLHPIEPTTLTRH
LPEGAPVLVCDPEKVRTRAADLIKTGREFLEASWSTAAVGGDAPIDLEAL
GASGFVTFEEAREAAREGGHPWWTLSQLSDESAVELDIRSAPSARGSQHN
LEEIFAMLRAHVATGGYAAVVTPGIGTAHRVVEQLGEADTAATILEPGTA
PKAGVVGVLKGPLCSGVVLPGANLVIITETDLTGNRVTKRRNVPLALTAG
DLVVHDQHGIGKFVEMTERVVGGARREYLVLEYTDKLYVPMDSLDQLSRY
VPSLSRLGGSDWANTKTKARRAVREIASELVALYAKRQSAPGHAFGPDTP
WQAEMEDAFGFTETIDQLTAIQEVKSDMEKPVPMDRVICGDVGYGKTEIA
VRAAFKAVQDGKQVAVLVPTTLLADQHLQTFTNRMAGFPVTVKGLSRFTD
PAESRAVIEGLKDGSVDVVIGTHRLLQTGVTWKDLGLIIVDEEQRFGVEH
KEHIKSMRTHVDVLTMSATPIPRTLEMSLAGIREMSTILTPPEERYPVLT
YVGPHDDKQVAAALRRELLRDGQAFYIHNRVRTIDEAAARVRQLVPEARV
VVAHGQMNEETLEKTVEGFWNREYDILVCTTIVETGLDISNANTLIVERA
DTFGLSQLHQLRGRVGRSRERGYAYFLYPPNKPLTETAYDRLATIAQNNE
LGAGMAVAMKDLEIRGAGNVLGAEQSGHVAGVGFDLYVRLVGEAVEAYRA
AADGKDVRIDLPVDAHLPPEYIGSDRLRLEAYRRLAAAADDDAVASVVDE
LIDRYGPLPEPAQRLVAVARLRLLCREFGITEIGAVSASTVRLSPMVLPD
SAQLRLKRMYPGGHYRATTSTVQVPLPRAGEGVGAPRIRDLELVQWVAGL
VLVLNGKGQGDVDMSKFS
3D structure
PDB6acx Structural basis for nucleotide-mediated remodelling mechanism of Mycobacterium Mfd
ChainB
Resolution3.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B F639 F641 G673 Y674 G675 K676 T677 P822 F609 F611 G643 Y644 G645 K646 T647 P792
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003684 damaged DNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
GO:0000716 transcription-coupled nucleotide-excision repair, DNA damage recognition
GO:0006281 DNA repair
GO:0006355 regulation of DNA-templated transcription
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6acx, PDBe:6acx, PDBj:6acx
PDBsum6acx
PubMed
UniProtA0R3C5

[Back to BioLiP]