Structure of PDB 5zyn Chain B

Receptor sequence
>5zynB (length=471) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
ASMKQPVVVIGSGLAGLTTSNRLISKYRIPVVLLDKAASIGGNSIKASSG
INGAHTDTQQNLKVMDTPELFLKDTLHSAKGRGVPSLMDKLTKESKSAIR
WLQTEFDLKLDLLAQLGGHSVPRTHRSSGKLPPGFEIVQALSKKLKDISS
KDSNLVQIMLNSEVVDIELDNQGHVTGVVYMDENGNRKIMKSHHVVFCSG
GFGYSKEMLKEYSPNLIHLPTTNGKQTTGDGQKILSKLGAELIDMDQVQV
HPTGFIDPNDRENNWKFLAAEALRGLGGILLHPTTGRRFTNELSTRDTVT
MEIQSKCPKNDNRALLVMSDKVYENYTNNINFYMSKNLIKKVSINDLIRQ
YDLQTTASELVTELKSYSDVNTKDTFDRPLIINAFDKDISTESTVYVGEV
TPVVHFTMGGVKINEKSQVIKKNSESVLSNGIFAAGEVSGGVHGANRLGG
SSLLECVVFGKTAADNIAKLY
3D structure
PDB5zyn Molecular basis of maintaining an oxidizing environment under anaerobiosis by soluble fumarate reductase.
ChainB
Resolution1.75 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) L146 Q279 H281 L298 E301 R304 R326 H435 F436 R477
Catalytic site (residue number reindexed from 1) L116 Q249 H251 L268 E271 R274 R296 H405 F406 R447
Enzyme Commision number 1.3.1.6: fumarate reductase (NADH).
Interaction with ligand
Gene Ontology
Molecular Function
GO:0010181 FMN binding
GO:0016156 fumarate reductase (NADH) activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0034975 protein folding in endoplasmic reticulum
GO:0046443 FAD metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5zyn, PDBe:5zyn, PDBj:5zyn
PDBsum5zyn
PubMed30451826
UniProtP21375|OSM1_YEAST Fumarate reductase 2 (Gene Name=OSM1)

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