Structure of PDB 5zln Chain B

Receptor sequence

>5zlnB (length=753) Species: 10090 (Mus musculus) [Search protein sequence]

TLPAFLPCELKPHGLVDCNWLFLKSVPRFSAAASCSNITRLSLISNRIHH
LHNSDFVHLSNLRQLNLKWNCPPTGLSPLHFSCHMTIEPRTFLAMRTLEE
LNLSYNGITTVPRLPSSLVNLSLSHTNILVLDANSLAGLYSLRVLFMDGN
CYYKNPCTGAVKVTPGALLGLSNLTHLSLKYNNLTKVPRQLPPSLEYLLV
SYNLIVKLGPEDLANLTSLRVLDVGGNCRRCDHAPNPCIECGQKSLHLHP
ETFHHLSHLEGLVLKDSSLHTLNSSWFQGLVNMSVLDLSENFLYESIQHT
NAFQNLTRLRKLNLSFNYRKKVSFARLHLASSFKNLVSLQELNMNGIFFR
SLNKYTLRWLADLPKLHTLHLQMNFINQAQLSIFGTFRALRFVDLSDNRI
SGPSTLSKNFMDRCKNFKFTMDLSRNNLVTIKPEMFVQLSRLQCLSLSHN
SIAQAVQGSQFLPLTNLQVLDLSHNKLDLYHWKSFSELPQLQALDLSYNS
QPFSMKGIGHNFSFVAHLSMLHSLSLAHNDIHTRVSSHLNSNSVRFLDFS
GNGMGRMWDEGGLYLHFFQGLSGLLKLDLSQNNLHILRPQNLDNLPKSLK
LLSLRDNYLSFFQWTSLSFLPNLEVLDLAGNQLKALTNGTLPNGTLLQKL
DVSSNSIVSVVPAFFALAVELKEVNLSHNILKTVDRSWFGPIVMNLTVLD
VRSNPLHCACGAAFVDLLLEVQTKVPGLANGVKCGSPGQLQGRSIFAQDL
RLC

3D structure

PDB

5zln Structural basis for species-specific activation of mouse Toll-like receptor 9

Chain

Resolution

2.3 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	B	R613 H642 S667 F668	R556 H585 S610 F611
BS02	dna	B	W47 S72 R74 H77 W96 P99 S104 P105 L106 F108 Y180 Y208 Y229 N263	W20 S45 R47 H50 W69 P72 S77 P78 L79 F81 Y153 Y181 Y202 N236
BS03	dna	B	D535 Y537 G566 H567 R591 V592	D478 Y480 G509 H510 R534 V535
BS04	dna	B	D259 H260 Y345 K348 V349 S350 F351 A352 F375 R377 F402	D232 H233 Y318 K321 V322 S323 F324 A325 F348 R350 F375

External links

PDB	RCSB:5zln, PDBe:5zln, PDBj:5zln
PDBsum	5zln
PubMed	29961984
UniProt	Q9EQU3\|TLR9_MOUSE Toll-like receptor 9 (Gene Name=Tlr9)

[Back to BioLiP]