Structure of PDB 5zfx Chain B

Receptor sequence
>5zfxB (length=248) Species: 6198 (Opisthorchis viverrini) [Search protein sequence]
RKFFVGGNWKMNGSKKENDKLIEMLTHAKIDPNTEVLVAPPALYLPSVRE
KLDKRFHVAAQNCYKVPSGAFTGEVSPAMLKDVGCDWVILGHSERRHILL
ETDQLVGEKTNHAISAGVNVIACIGEKLEEREAGKTEEVCFRQMEAIRKN
LSSADMWNHIVIAYEPVWAIGTGKTATEQQAQEVHLAVRRWMEEKVSPAV
AKSIRIIYGGSVTAANCRTLAKQPDVDGFLVGGASLKPDFIEICNANA
3D structure
PDB5zfx Structural Analysis of an Epitope Candidate of Triosephosphate Isomerase in Opisthorchis viverrini.
ChainB
Resolution1.751 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N12 K14 H96 E98 E169 G175 S215
Catalytic site (residue number reindexed from 1) N8 K10 H92 E94 E165 G171 S211
Enzyme Commision number 5.3.1.1: triose-phosphate isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B E27 H31 E23 H27
BS02 MG B A173 T176 K178 A169 T172 K174
Gene Ontology
Molecular Function
GO:0004807 triose-phosphate isomerase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006094 gluconeogenesis
GO:0006096 glycolytic process
GO:0019563 glycerol catabolic process
GO:0046166 glyceraldehyde-3-phosphate biosynthetic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:5zfx, PDBe:5zfx, PDBj:5zfx
PDBsum5zfx
PubMed30305716
UniProtA0A074Z863

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