Structure of PDB 5z9p Chain B

Receptor sequence
>5z9pB (length=183) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
LEGLEAVRKRPGMYIGSTSERGLHHLVWEIVDNSIDEALAGYANQIEVVI
EKDNWIKVTDNGRGIPVDIQGRPAVEVILTSSVVNALSQDLEVYVHRNET
IYHQAYKKGVPQFDLKEVGTTDKTGTVIRFKADGEIFTETTVYNYETLQQ
RIRELAFLNKGIQITLRDERDEENVREDSYHYE
3D structure
PDB5z9p Identification of an auxiliary druggable pocket in the DNA gyrase ATPase domain using fragment probes
ChainB
Resolution1.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AX7 B N54 I86 L103 N33 I65 L79
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006265 DNA topological change

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Molecular Function
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Biological Process
External links
PDB RCSB:5z9p, PDBe:5z9p, PDBj:5z9p
PDBsum5z9p
PubMed30429968
UniProtP0A0K8|GYRB_STAAU DNA gyrase subunit B (Gene Name=gyrB)

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