Structure of PDB 5z9f Chain B

Receptor sequence
>5z9fB (length=187) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
LDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHA
DNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLGVGVSVVNALSQKLELV
IQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFE
YEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEG
3D structure
PDB5z9f Identification of an auxiliary druggable pocket in the DNA gyrase ATPase domain using fragment probes
ChainB
Resolution1.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AX7 B R20 H147 E174 R5 H114 E141
BS02 0R0 B V43 N46 E50 I78 V120 V167 V28 N31 E35 I63 V87 V134
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006265 DNA topological change

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Molecular Function
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Biological Process
External links
PDB RCSB:5z9f, PDBe:5z9f, PDBj:5z9f
PDBsum5z9f
PubMed30429968
UniProtP0AES6|GYRB_ECOLI DNA gyrase subunit B (Gene Name=gyrB)

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