Structure of PDB 5yzc Chain B

Receptor sequence
>5yzcB (length=367) Species: 645098 (Measles virus strain Ichinose-B95a) [Search protein sequence]
GVVLAGAALGVATAAQITAGIALHQSMLNSQAIDNLRASLETTNQAIEAI
RQAGQEMILAVQGVQDYINNELIPSMNQLSCDLIGQKLGLKLLRYYTEIL
SLFGPSLRDPISAEISIQALSYALGGDINKVLEKLGYSGGDLLGILESRG
IKARITHVDTESYFIVLSIAYPTLSEIKGVIVHRLEGVSYNIGSQEWYTT
VPKYVATQGYLISNFDESSCTFMPEGTVCSQNALYPMSPLLQECLRGSTK
SCARTLVSGSFGNRFILSQGNLIANCASILCKCYTTGTIINQDPDKILTY
IAADHCPVVEVNGVTIQVGSRRYPDAVYLHRIDLGPPISLERLDVGTNLG
NAIAKLEDAKELLESSD
3D structure
PDB5yzc Structures of the prefusion form of measles virus fusion protein in complex with inhibitors.
ChainB
Resolution2.334 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 95C B T369 L370 P451 I452 S453 N462 T255 L256 P337 I338 S339 N348 PDBbind-CN: -logKd/Ki=5.52,IC50=3.0uM
Gene Ontology
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane

View graph for
Biological Process
External links
PDB RCSB:5yzc, PDBe:5yzc, PDBj:5yzc
PDBsum5yzc
PubMed29463726
UniProtQ786F3|FUS_MEASC Fusion glycoprotein F0 (Gene Name=F)

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