Structure of PDB 5ywv Chain B

Receptor sequence
>5ywvB (length=224) Species: 10090 (Mus musculus) [Search protein sequence]
LPHGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPP
PVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLA
ILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDS
IAALKALEQASSSRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQW
KPQALLQWVDEHARPFSTVKPMYG
3D structure
PDB5ywv Structural basis for overhang excision and terminal unwinding of DNA duplexes by TREX1
ChainB
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.11.2: exodeoxyribonuclease III.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B E20 A21 G23 L24 P25 A81 I84 H124 N125 R128 Y129 I156 S176 Y177 S178 L179 H195 E15 A16 G18 L19 P20 A76 I79 H119 N120 R123 Y124 I151 S166 Y167 S168 L169 H185
BS02 MG B D18 E20 D200 D13 E15 D190
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008408 3'-5' exonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:5ywv, PDBe:5ywv, PDBj:5ywv
PDBsum5ywv
PubMed29734329
UniProtQ91XB0|TREX1_MOUSE Three-prime repair exonuclease 1 (Gene Name=Trex1)

[Back to BioLiP]