Structure of PDB 5ywr Chain B

Receptor sequence
>5ywrB (length=87) Species: 9606 (Homo sapiens) [Search protein sequence]
SGFKCPICSKSVASDEMEMHFIMCLSKPRLSYNDDVLTKDAGECVICLEE
LLQGDTIARLPCLCIYHKSCIDSWFEVNRSCPEHPAD
3D structure
PDB5ywr Structural insights into the nanomolar affinity of RING E3 ligase ZNRF1 for Ube2N and its functional implications.
ChainB
Resolution1.47 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C184 C187 H207 C210 C44 C47 H67 C70
BS02 ZN B C145 C148 H160 C164 C5 C8 H20 C24
BS03 ZN B C202 C204 C221 H224 C62 C64 C81 H84
External links
PDB RCSB:5ywr, PDBe:5ywr, PDBj:5ywr
PDBsum5ywr
PubMed29626159
UniProtQ8ND25|ZNRF1_HUMAN E3 ubiquitin-protein ligase ZNRF1 (Gene Name=ZNRF1)

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