Structure of PDB 5yvj Chain B

Receptor sequence
>5yvjB (length=589) Species: 11070 (dengue virus type 4) [Search protein sequence]
LSEGVYRIMQRGLFGKTQVGVGIHMEGVFHTMWHVTRGSVICHETGRLEP
SWADVRNDMISYGGGWRLGDKWDKEEDVQVLAIEPGKNPKHVQTKPGLFK
TLGAVTLDFKPGTAGSPIINKKGKVIGLYGNGVSAITQAERIGEPDYEVD
EDIFRKKRLTIMDLHPGAGKTKRILPSIVREALKRRLRTLILAPTRVVAA
EMEEALRGLPIRYQTPAVKSEHTGREIVDLMCHATFTTRLLSSTRVPNYN
LIVMDEAHFTDPCSVAARGYISTRVEMGEAAAIFMTATPPGSIDPFPQSN
SPIEDIEREIPERSWNTGFDWITDYQGKTVWFVPSIKAGNDIANCLRKSG
KKVIQLSRKTFDTEYPKTKLTDWDFVVTTDISEMGANFRAGRVIDPRRCL
KPVILTDGPERVILAGPIPVTPASAAQRRGRIGRNPAQEDDQYVFSGDPL
KNDEDHAHWTEAKMLLDNIYTPEGIIPTLFGPEREKTQAIDGEFRLRGEQ
RKTFVELMRRGDLPVWLSYKVASAGISYKDREWCFTGERNNQILEENMEV
EIWTREGEKKKLRPKWLDARVYADPMALKDFKEFASGRK
3D structure
PDB5yvj Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
ChainB
Resolution2.508 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.4.21.91: flavivirin.
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B S19 E20 G21 V22 Y23 R24 M26 R28 F46 T53 V57 C59 D94 Q96 H108 N141 K142 S2 E3 G4 V5 Y6 R7 M9 R11 F29 T36 V40 C42 D77 Q79 H91 N120 K121
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:5yvj, PDBe:5yvj, PDBj:5yvj
PDBsum5yvj
PubMed
UniProtF8TEL4

[Back to BioLiP]