Structure of PDB 5ypc Chain B

Receptor sequence
>5ypcB (length=50) Species: 9606 (Homo sapiens) [Search protein sequence]
FEEEDVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPS
3D structure
PDB5ypc Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
ChainB
Resolution1.962 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
3.6.4.10: non-chaperonin molecular chaperone ATPase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B C4 C7 C30 C8 C11 C34
BS02 ZN B C18 C21 H36 H39 C22 C25 H40 H43
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:5ypc, PDBe:5ypc, PDBj:5ypc
PDBsum5ypc
PubMed30120248
UniProtP11021|BIP_HUMAN Endoplasmic reticulum chaperone BiP (Gene Name=HSPA5);
Q13501|SQSTM_HUMAN Sequestosome-1 (Gene Name=SQSTM1)

[Back to BioLiP]